| 04:04 | CM458 | Copa Airlines | To Tocumen International Airport PTY | 04:04 04:04 | — | 0 | Departed |
| 04:30 | AV575 | Avianca | To El Salvador International Airport Saint Óscar Arnulfo Romero y Galdámez SAL | 04:30 | — | — | Cancelled |
| 04:30 | TA575 | Avianca El Salvador | To El Salvador International Airport Saint Óscar Arnulfo Romero y Galdámez SAL | 04:30 04:30 | — | 0 | Departed |
| 06:15 | H53044 | I-Fly | To Juan Manuel Gálvez International Airport RTB | 06:15 | — | — | Scheduled |
| 06:15 | UA2484 | United Airlines | To George Bush Intercontinental Airport IAH | 06:15 06:25 | — | +10 | Departed |
| 06:30 | 5U320 | Transportes Aéreos Guatemaltecos | From La Aurora International Airport GUA | 05:30 | 06:30 06:31 | +1 | Arrived |
| 07:00 | H53005 | I-Fly | From Toncontín Airport TGU | 06:15 | 07:00 06:53 | -7 | Arrived |
| 08:00 | H5319 | I-Fly | To La Aurora International Airport GUA | 08:00 | — | — | Scheduled |
| 08:10 | H53004 | I-Fly | To Toncontín Airport TGU | 08:10 08:13 | — | +3 | Departed |
| 08:10 | S060 | Slok Air Gambia | From Golosón International Airport LCE | 07:30 | 08:10 07:57 | -13 | Arrived |
| 08:30 | AV536 | Avianca | From El Salvador International Airport Saint Óscar Arnulfo Romero y Galdámez SAL | 07:35 | 08:30 | — | Cancelled |
| 08:30 | TA536 | Avianca El Salvador | From El Salvador International Airport Saint Óscar Arnulfo Romero y Galdámez SAL | 07:35 | 08:30 08:05 | -25 | Arrived |
| 08:45 | H53013 | I-Fly | From Juan Manuel Gálvez International Airport RTB | 08:05 | 08:45 08:46 | +1 | Arrived |
| 08:45 | S085 | Slok Air Gambia | From Juan Manuel Gálvez International Airport RTB | 08:00 | 08:45 | — | Not reported |
| 09:25 | AV537 | Avianca | To El Salvador International Airport Saint Óscar Arnulfo Romero y Galdámez SAL | 09:25 09:35 | — | +10 | Departed |
| 09:25 | H53026 | I-Fly | To Juan Manuel Gálvez International Airport RTB | 09:25 09:43 | — | +18 | Departed |
| 09:25 | TA537 | Avianca El Salvador | To El Salvador International Airport Saint Óscar Arnulfo Romero y Galdámez SAL | 09:25 09:30 | — | +5 | Departed |
| 09:30 | S088 | Slok Air Gambia | To Juan Manuel Gálvez International Airport RTB | 09:30 09:19 | — | -11 | Departed |
| 11:16 | DL1782 | Delta Air Lines | From Hartsfield Jackson Atlanta International Airport ATL | 09:59 | 11:16 08:23 | -173 | Arrived |
| 11:25 | 5D674 | Dutchbird | From Mexico City Benito Juárez International Airport MEX | 08:40 | 11:25 09:01 | -144 | Arrived |
| 11:25 | AM674 | Aeroméxico | From Mexico City Benito Juárez International Airport MEX | 08:40 | 11:25 | — | Cancelled |
| 11:32 | UA1487 | United Airlines | From George Bush Intercontinental Airport IAH | 09:45 | 11:32 09:15 | -137 | Arrived |
| 12:25 | 5D675 | Dutchbird | To Mexico City Benito Juárez International Airport MEX | 12:25 12:38 | — | +13 | Departed |
| 12:25 | AM675 | Aeroméxico | To Mexico City Benito Juárez International Airport MEX | 12:25 12:35 | — | +10 | Departed |
| 12:30 | AA939 | American Airlines | From Miami International Airport MIA | 12:06 | 12:30 12:32 | +2 | Arrived |
| 12:35 | UA1242 | United Airlines | To George Bush Intercontinental Airport IAH | 12:35 12:55 | — | +20 | Departed |
| 12:41 | DL1805 | Delta Air Lines | To Hartsfield Jackson Atlanta International Airport ATL | 12:41 13:08 | — | +27 | Departed |
| 12:44 | CM286 | Copa Airlines | From Tocumen International Airport PTY | 11:34 | 12:44 | — | Cancelled |
| 13:30 | AA1312 | American Airlines | To Miami International Airport MIA | 13:30 16:06 | — | +156 | Departed |
| 13:46 | CM287 | Copa Airlines | To Tocumen International Airport PTY | 13:46 13:44 | — | -2 | Departed |
| 13:50 | M6724 | Amerijet International | From Norman Manley International Airport KIN | 12:45 | 13:50 | — | Cancelled |
| 14:40 | W85240 | Cargojet Airways | From Juan Santamaría International Airport SJO | 13:00 | 14:40 | — | Cancelled |
| 15:15 | H53027 | I-Fly | From Juan Manuel Gálvez International Airport RTB | 14:30 | 15:15 15:05 | -10 | Arrived |
| 15:20 | M6724 | Amerijet International | To Miami International Airport MIA | 15:20 18:23 | — | +183 | Departed |
| 15:45 | S089 | Slok Air Gambia | From Juan Manuel Gálvez International Airport RTB | 15:00 | 15:45 15:09 | -36 | Arrived |
| 15:55 | H53010 | I-Fly | To Juan Manuel Gálvez International Airport RTB | 15:55 16:11 | — | +16 | Departed |
| 16:00 | S065 | Slok Air Gambia | To Golosón International Airport LCE | 16:00 16:24 | — | +24 | Departed |
| 16:00 | S086 | Slok Air Gambia | To Juan Manuel Gálvez International Airport RTB | 16:00 | — | — | Not reported |
| 16:00 | W85236 | Cargojet Airways | To Miami International Airport MIA | 16:00 | — | — | Cancelled |
| 17:15 | H53007 | I-Fly | From Toncontín Airport TGU | 16:30 | 17:15 17:04 | -11 | Arrived |
| 17:25 | FX5504 | Federal Express | To Miami International Airport MIA | 17:25 17:23 | — | -2 | Departed |
| 17:31 | FX5504 | Federal Express | To Miami International Airport MIA | 17:31 17:31 | — | 0 | Departed |
| 18:00 | H53006 | I-Fly | To Toncontín Airport TGU | 18:00 17:59 | — | -1 | Departed |
| 18:15 | H53029 | I-Fly | From Juan Manuel Gálvez International Airport RTB | 17:35 | 18:15 | — | Not reported |
| 18:45 | AV534 | Avianca | From El Salvador International Airport Saint Óscar Arnulfo Romero y Galdámez SAL | 17:50 | 18:45 | — | Cancelled |
| 18:45 | TA534 | Avianca El Salvador | From El Salvador International Airport Saint Óscar Arnulfo Romero y Galdámez SAL | 17:50 | 18:45 18:29 | -16 | Arrived |
| 20:10 | AV535 | Avianca | To El Salvador International Airport Saint Óscar Arnulfo Romero y Galdámez SAL | 20:10 | — | — | Cancelled |
| 20:10 | TA535 | Avianca El Salvador | To El Salvador International Airport Saint Óscar Arnulfo Romero y Galdámez SAL | 20:10 20:03 | — | -7 | Departed |
| 23:25 | AV574 | Avianca | From El Salvador International Airport Saint Óscar Arnulfo Romero y Galdámez SAL | 22:30 | 23:25 | — | Cancelled |
| 23:25 | TA574 | Avianca El Salvador | From El Salvador International Airport Saint Óscar Arnulfo Romero y Galdámez SAL | 22:30 | 23:25 22:59 | -26 | Arrived |