| 04:03 | CM458 | Copa Airlines | To Tocumen International Airport PTY | 04:03 04:13 | — | +10 | Departed |
| 04:30 | AV575 | Avianca | To El Salvador International Airport Saint Óscar Arnulfo Romero y Galdámez SAL | 04:30 04:40 | — | +10 | Departed |
| 04:30 | TA575 | Avianca El Salvador | To El Salvador International Airport Saint Óscar Arnulfo Romero y Galdámez SAL | 04:30 04:36 | — | +6 | Departed |
| 06:15 | UA2484 | United Airlines | To George Bush Intercontinental Airport IAH | 06:15 06:30 | — | +15 | Departed |
| 06:30 | 5U320 | Transportes Aéreos Guatemaltecos | From La Aurora International Airport GUA | 05:30 | 06:30 06:25 | -5 | Arrived |
| 07:00 | H53005 | ALL / N/A | From Toncontín Airport TGU | 06:15 | 07:00 06:56 | -4 | Arrived |
| 07:52 | F9363 | Frontier Airlines | From Orlando International Airport MCO | 07:06 | 07:52 06:03 | -109 | Arrived |
| 08:00 | H5319 | ALL / N/A | To La Aurora International Airport GUA | 08:00 | — | — | Scheduled |
| 08:10 | S060 | Slok Air Gambia | From Golosón International Airport LCE | 07:30 | 08:10 | — | Not reported |
| 08:30 | AV536 | Avianca | From El Salvador International Airport Saint Óscar Arnulfo Romero y Galdámez SAL | 07:35 | 08:30 | — | Cancelled |
| 08:30 | H53036 | ALL / N/A | To Toncontín Airport TGU | 08:30 08:35 | — | +5 | Departed |
| 08:30 | TA536 | Avianca El Salvador | From El Salvador International Airport Saint Óscar Arnulfo Romero y Galdámez SAL | 07:35 | 08:30 08:17 | -13 | Arrived |
| 08:45 | S085 | Slok Air Gambia | From Juan Manuel Gálvez International Airport RTB | 08:00 | 08:45 | — | Not reported |
| 08:50 | H53021 | ALL / N/A | From Juan Manuel Gálvez International Airport RTB | 08:05 | 08:50 08:41 | -9 | Arrived |
| 09:07 | F9362 | Frontier Airlines | To Orlando International Airport MCO | 09:07 09:58 | — | +51 | Departed |
| 09:25 | AV537 | Avianca | To El Salvador International Airport Saint Óscar Arnulfo Romero y Galdámez SAL | 09:25 | — | — | Cancelled |
| 09:25 | TA537 | Avianca El Salvador | To El Salvador International Airport Saint Óscar Arnulfo Romero y Galdámez SAL | 09:25 09:31 | — | +6 | Departed |
| 09:30 | H53026 | ALL / N/A | To Juan Manuel Gálvez International Airport RTB | 09:30 09:37 | — | +7 | Departed |
| 09:30 | S088 | Slok Air Gambia | To Juan Manuel Gálvez International Airport RTB | 09:30 | — | — | Scheduled |
| 10:00 | G66126 | ALL / N/A | From Alexandria International Airport AEX | 08:22 | 10:00 07:53 | -127 | Arrived |
| 10:20 | M6766 | Amerijet International | To Miami International Airport MIA | 10:20 | — | — | Not reported |
| 10:44 | G66127 | ALL / N/A | To Alexandria International Airport AEX | 10:44 10:47 | — | +3 | Departed |
| 10:50 | M6765 | Amerijet International | From Miami International Airport MIA | 10:30 | 10:50 11:05 | +15 | Arrived |
| 11:08 | DL1782 | Delta Air Lines | From Hartsfield Jackson Atlanta International Airport ATL | 09:59 | 11:08 08:32 | -156 | Arrived |
| 11:25 | 5D674 | ALL / N/A | From Mexico City Benito Juárez International Airport MEX | 08:50 | 11:25 09:25 | -120 | Arrived |
| 11:25 | AM674 | Aeroméxico | From Mexico City Benito Juárez International Airport MEX | 08:50 | 11:25 | — | Cancelled |
| 11:32 | UA1487 | United Airlines | From George Bush Intercontinental Airport IAH | 09:45 | 11:32 09:25 | -127 | Arrived |
| 12:20 | M6764 | Amerijet International | To Miami International Airport MIA | 12:20 | — | — | Cancelled |
| 12:25 | 5D675 | ALL / N/A | To Mexico City Benito Juárez International Airport MEX | 12:25 12:33 | — | +8 | Departed |
| 12:25 | AM675 | Aeroméxico | To Mexico City Benito Juárez International Airport MEX | 12:25 | — | — | Cancelled |
| 12:30 | AA939 | American Airlines | From Miami International Airport MIA | 12:06 | 12:30 10:19 | -131 | Arrived |
| 12:35 | UA1242 | United Airlines | To George Bush Intercontinental Airport IAH | 12:35 13:13 | — | +38 | Departed |
| 12:41 | DL1805 | Delta Air Lines | To Hartsfield Jackson Atlanta International Airport ATL | 12:41 12:57 | — | +16 | Departed |
| 12:44 | CM286 | Copa Airlines | From Tocumen International Airport PTY | 11:34 | 12:44 12:30 | -14 | Arrived |
| 13:30 | AA1312 | American Airlines | To Miami International Airport MIA | 13:30 13:26 | — | -4 | Departed |
| 13:30 | G66127 | ALL / N/A | To Alexandria International Airport AEX | 13:30 | — | — | Scheduled |
| 13:45 | CM287 | Copa Airlines | To Tocumen International Airport PTY | 13:45 13:41 | — | -4 | Departed |
| 14:40 | W85240 | Cargojet Airways | From Juan Santamaría International Airport SJO | 13:00 | 14:40 | — | Cancelled |
| 14:45 | H53027 | ALL / N/A | From Juan Manuel Gálvez International Airport RTB | 14:00 | 14:45 14:30 | -15 | Arrived |
| 15:25 | H53020 | ALL / N/A | To Juan Manuel Gálvez International Airport RTB | 15:25 15:31 | — | +6 | Departed |
| 15:45 | S089 | Slok Air Gambia | From Juan Manuel Gálvez International Airport RTB | 15:00 | 15:45 15:21 | -24 | Arrived |
| 16:00 | S065 | Slok Air Gambia | To Golosón International Airport LCE | 16:00 16:26 | — | +26 | Departed |
| 16:00 | S086 | Slok Air Gambia | To Juan Manuel Gálvez International Airport RTB | 16:00 | — | — | Scheduled |
| 16:00 | W85236 | Cargojet Airways | To Miami International Airport MIA | 16:00 | — | — | Not reported |
| 17:15 | H53015 | ALL / N/A | From Toncontín Airport TGU | 16:30 | 17:15 | — | Scheduled |
| 21:38 | UA1474 | United Airlines | From Newark Liberty International Airport EWR | 19:01 | 21:38 18:05 | -213 | Arrived |
| 21:57 | UA432 | United Airlines | From George Bush Intercontinental Airport IAH | 20:10 | 21:57 20:02 | -115 | Arrived |
| 23:10 | UA2450 | United Airlines | To Newark Liberty International Airport EWR | 23:10 23:51 | — | +41 | Departed |
| 23:25 | AV574 | Avianca | From El Salvador International Airport Saint Óscar Arnulfo Romero y Galdámez SAL | 22:30 | 23:25 | — | Cancelled |
| 23:25 | TA574 | Avianca El Salvador | From El Salvador International Airport Saint Óscar Arnulfo Romero y Galdámez SAL | 22:30 | 23:25 22:56 | -29 | Arrived |
| 23:29 | CM457 | Copa Airlines | From Tocumen International Airport PTY | 22:19 | 23:29 23:14 | -15 | Arrived |