| 04:03 | CM458 | Copa Airlines | To Tocumen International Airport PTY | 04:03 04:15 | — | +12 | Departed |
| 04:30 | AV575 | Avianca | To El Salvador International Airport Saint Óscar Arnulfo Romero y Galdámez SAL | 04:30 04:40 | — | +10 | Departed |
| 04:30 | TA575 | Avianca El Salvador | To El Salvador International Airport Saint Óscar Arnulfo Romero y Galdámez SAL | 04:30 04:31 | — | +1 | Departed |
| 05:50 | M6775 | Amerijet International | From Miami International Airport MIA | 05:30 | 05:50 | — | Cancelled |
| 06:15 | UA2484 | United Airlines | To George Bush Intercontinental Airport IAH | 06:15 06:21 | — | +6 | Departed |
| 07:20 | M6774 | Amerijet International | To Miami International Airport MIA | 07:20 | — | — | Cancelled |
| 08:10 | S060 | Slok Air Gambia | From Golosón International Airport LCE | 07:30 | 08:10 | — | Not reported |
| 08:45 | S085 | Slok Air Gambia | From Juan Manuel Gálvez International Airport RTB | 08:00 | 08:45 | — | Scheduled |
| 08:50 | H53013 | ALL / N/A | From Juan Manuel Gálvez International Airport RTB | 08:05 | 08:50 08:40 | -10 | Arrived |
| 09:30 | H53026 | ALL / N/A | To Juan Manuel Gálvez International Airport RTB | 09:30 09:43 | — | +13 | Departed |
| 09:30 | S088 | Slok Air Gambia | To Juan Manuel Gálvez International Airport RTB | 09:30 | — | — | Scheduled |
| 10:00 | S062 | Slok Air Gambia | From Golosón International Airport LCE | 09:30 | 10:00 09:48 | -12 | Arrived |
| 11:16 | DL1782 | Delta Air Lines | From Hartsfield Jackson Atlanta International Airport ATL | 09:59 | 11:16 10:21 | -55 | Arrived |
| 11:25 | 5D674 | ALL / N/A | From Mexico City Benito Juárez International Airport MEX | 08:50 | 11:25 10:12 | -73 | Arrived |
| 11:25 | AM674 | Aeroméxico | From Mexico City Benito Juárez International Airport MEX | 08:50 | 11:25 | — | Scheduled |
| 11:26 | B62089 | JetBlue Airways | From Fort Lauderdale Hollywood International Airport FLL | 11:00 | 11:26 10:26 | -60 | Arrived |
| 11:30 | M6776 | Amerijet International | From Tocumen International Airport PTY | 10:25 | 11:30 | — | Scheduled |
| 11:32 | UA1487 | United Airlines | From George Bush Intercontinental Airport IAH | 09:45 | 11:32 09:32 | -120 | Arrived |
| 12:25 | 5D675 | ALL / N/A | To Mexico City Benito Juárez International Airport MEX | 12:25 12:37 | — | +12 | Departed |
| 12:25 | AM675 | Aeroméxico | To Mexico City Benito Juárez International Airport MEX | 12:25 12:20 | — | -5 | Departed |
| 12:30 | AA939 | American Airlines | From Miami International Airport MIA | 12:06 | 12:30 12:09 | -21 | Arrived |
| 12:35 | UA1242 | United Airlines | To George Bush Intercontinental Airport IAH | 12:35 13:47 | — | +72 | Departed |
| 12:41 | DL1805 | Delta Air Lines | To Hartsfield Jackson Atlanta International Airport ATL | 12:41 13:16 | — | +35 | Departed |
| 12:44 | CM286 | Copa Airlines | From Tocumen International Airport PTY | 11:34 | 12:44 12:35 | -9 | Arrived |
| 13:00 | M6776 | Amerijet International | To Miami International Airport MIA | 13:00 | — | — | Cancelled |
| 13:10 | H53035 | ALL / N/A | From Toncontín Airport TGU | 12:30 | 13:10 | — | Scheduled |
| 13:30 | AA1312 | American Airlines | To Miami International Airport MIA | 13:30 13:42 | — | +12 | Departed |
| 13:35 | B62090 | JetBlue Airways | To Fort Lauderdale Hollywood International Airport FLL | 13:35 13:55 | — | +20 | Departed |
| 13:35 | H53015 | ALL / N/A | From Toncontín Airport TGU | 12:50 | 13:35 | — | Not reported |
| 13:45 | CM287 | Copa Airlines | To Tocumen International Airport PTY | 13:45 14:08 | — | +23 | Departed |
| 13:45 | H5322 | ALL / N/A | From La Aurora International Airport GUA | 12:45 | 13:45 | — | Scheduled |
| 14:20 | H53027 | ALL / N/A | From Juan Manuel Gálvez International Airport RTB | 13:35 | 14:20 14:07 | -13 | Arrived |
| 14:25 | H5319 | ALL / N/A | To La Aurora International Airport GUA | 14:25 | — | — | Scheduled |
| 15:00 | H53010 | ALL / N/A | To Juan Manuel Gálvez International Airport RTB | 15:00 15:05 | — | +5 | Departed |
| 15:15 | H53036 | ALL / N/A | To Toncontín Airport TGU | 15:15 16:03 | — | +48 | Departed |
| 15:20 | H53061 | ALL / N/A | From Juan Manuel Gálvez International Airport RTB | 14:40 | 15:20 | — | Not reported |
| 15:45 | H53014 | ALL / N/A | To Toncontín Airport TGU | 15:45 | — | — | Scheduled |
| 15:45 | S089 | Slok Air Gambia | From Juan Manuel Gálvez International Airport RTB | 15:00 | 15:45 15:28 | -17 | Arrived |
| 16:00 | S065 | Slok Air Gambia | To Golosón International Airport LCE | 16:00 | — | — | Scheduled |
| 16:00 | S086 | Slok Air Gambia | To Juan Manuel Gálvez International Airport RTB | 16:00 | — | — | Scheduled |
| 16:47 | WH916 | WebJet Linhas Aéreas | From El Salvador International Airport Saint Óscar Arnulfo Romero y Galdámez SAL | 15:45 | 16:47 | — | Not reported |
| 18:02 | CM915 | Copa Airlines | To Tocumen International Airport PTY | 18:02 | — | — | Scheduled |
| 18:02 | WH915 | WebJet Linhas Aéreas | To Tocumen International Airport PTY | 18:02 | — | — | Scheduled |
| 18:45 | AV534 | Avianca | From El Salvador International Airport Saint Óscar Arnulfo Romero y Galdámez SAL | 17:50 | 18:45 | — | Cancelled |
| 18:45 | TA534 | Avianca El Salvador | From El Salvador International Airport Saint Óscar Arnulfo Romero y Galdámez SAL | 17:50 | 18:45 18:20 | -25 | Arrived |
| 20:10 | AV535 | Avianca | To El Salvador International Airport Saint Óscar Arnulfo Romero y Galdámez SAL | 20:10 | — | — | Cancelled |
| 20:10 | TA535 | Avianca El Salvador | To El Salvador International Airport Saint Óscar Arnulfo Romero y Galdámez SAL | 20:10 20:15 | — | +5 | Departed |
| 21:57 | UA432 | United Airlines | From George Bush Intercontinental Airport IAH | 20:10 | 21:57 19:45 | -132 | Arrived |
| 23:25 | AV574 | Avianca | From El Salvador International Airport Saint Óscar Arnulfo Romero y Galdámez SAL | 22:30 | 23:25 | — | Cancelled |
| 23:25 | TA574 | Avianca El Salvador | From El Salvador International Airport Saint Óscar Arnulfo Romero y Galdámez SAL | 22:30 | 23:25 22:51 | -34 | Arrived |