| 04:03 | CM458 | Copa Airlines | To Tocumen International Airport PTY | 04:03 | — | — | Cancelled |
| 04:30 | AV575 | Avianca | To El Salvador International Airport Saint Óscar Arnulfo Romero y Galdámez SAL | 04:30 04:40 | — | +10 | Departed |
| 04:30 | TA575 | Avianca El Salvador | To El Salvador International Airport Saint Óscar Arnulfo Romero y Galdámez SAL | 04:30 04:26 | — | -4 | Departed |
| 06:15 | UA2484 | United Airlines | To George Bush Intercontinental Airport IAH | 06:15 06:17 | — | +2 | Departed |
| 06:30 | 5U320 | Transportes Aéreos Guatemaltecos | From La Aurora International Airport GUA | 05:30 | 06:30 06:36 | +6 | Arrived |
| 07:00 | H53005 | ALL / N/A | From Toncontín Airport TGU | 06:15 | 07:00 06:46 | -14 | Arrived |
| 08:00 | H5319 | ALL / N/A | To La Aurora International Airport GUA | 08:00 | — | — | Scheduled |
| 08:10 | S060 | Slok Air Gambia | From Golosón International Airport LCE | 07:30 | 08:10 | — | Scheduled |
| 08:25 | F9363 | Frontier Airlines | From Orlando International Airport MCO | 07:38 | 08:25 07:12 | -73 | Arrived |
| 08:30 | AV536 | Avianca | From El Salvador International Airport Saint Óscar Arnulfo Romero y Galdámez SAL | 07:35 | 08:30 | — | Cancelled |
| 08:30 | H53036 | ALL / N/A | To Toncontín Airport TGU | 08:30 08:20 | — | -10 | Departed |
| 08:30 | TA536 | Avianca El Salvador | From El Salvador International Airport Saint Óscar Arnulfo Romero y Galdámez SAL | 07:35 | 08:30 08:16 | -14 | Arrived |
| 08:45 | S085 | Slok Air Gambia | From Juan Manuel Gálvez International Airport RTB | 08:00 | 08:45 | — | Scheduled |
| 08:50 | H53021 | ALL / N/A | From Juan Manuel Gálvez International Airport RTB | 08:05 | 08:50 08:32 | -18 | Arrived |
| 09:25 | AV537 | Avianca | To El Salvador International Airport Saint Óscar Arnulfo Romero y Galdámez SAL | 09:25 | — | — | Cancelled |
| 09:25 | TA537 | Avianca El Salvador | To El Salvador International Airport Saint Óscar Arnulfo Romero y Galdámez SAL | 09:25 09:19 | — | -6 | Departed |
| 09:30 | F9362 | Frontier Airlines | To Orlando International Airport MCO | 09:30 10:06 | — | +36 | Departed |
| 09:30 | H53026 | ALL / N/A | To Juan Manuel Gálvez International Airport RTB | 09:30 09:21 | — | -9 | Departed |
| 09:30 | S088 | Slok Air Gambia | To Juan Manuel Gálvez International Airport RTB | 09:30 | — | — | Scheduled |
| 10:50 | M6765 | Amerijet International | From Miami International Airport MIA | 10:30 | 10:50 11:14 | +24 | Arrived |
| 11:16 | DL1782 | Delta Air Lines | From Hartsfield Jackson Atlanta International Airport ATL | 09:58 | 11:16 08:34 | -162 | Arrived |
| 11:25 | 5D674 | ALL / N/A | From Mexico City Benito Juárez International Airport MEX | 08:50 | 11:25 09:21 | -124 | Arrived |
| 11:25 | AM674 | Aeroméxico | From Mexico City Benito Juárez International Airport MEX | 08:50 | 11:25 | — | Cancelled |
| 11:32 | UA1487 | United Airlines | From George Bush Intercontinental Airport IAH | 09:45 | 11:32 09:12 | -140 | Arrived |
| 12:20 | M6764 | Amerijet International | To Miami International Airport MIA | 12:20 | — | — | Cancelled |
| 12:25 | 5D675 | ALL / N/A | To Mexico City Benito Juárez International Airport MEX | 12:25 12:31 | — | +6 | Departed |
| 12:25 | AM675 | Aeroméxico | To Mexico City Benito Juárez International Airport MEX | 12:25 | — | — | Cancelled |
| 12:34 | AA939 | American Airlines | From Miami International Airport MIA | 12:11 | 12:34 12:08 | -26 | Arrived |
| 12:35 | UA1242 | United Airlines | To George Bush Intercontinental Airport IAH | 12:35 12:47 | — | +12 | Departed |
| 12:41 | DL1805 | Delta Air Lines | To Hartsfield Jackson Atlanta International Airport ATL | 12:41 12:59 | — | +18 | Departed |
| 12:44 | CM286 | Copa Airlines | From Tocumen International Airport PTY | 11:34 | 12:44 | — | Cancelled |
| 13:36 | AA1312 | American Airlines | To Miami International Airport MIA | 13:36 13:31 | — | -5 | Departed |
| 13:45 | CM287 | Copa Airlines | To Tocumen International Airport PTY | 13:45 | — | — | Cancelled |
| 14:40 | W85240 | Cargojet Airways | From Juan Santamaría International Airport SJO | 13:00 | 14:40 | — | Cancelled |
| 14:45 | H53027 | ALL / N/A | From Juan Manuel Gálvez International Airport RTB | 14:00 | 14:45 14:43 | -2 | Arrived |
| 15:25 | H53020 | ALL / N/A | To Juan Manuel Gálvez International Airport RTB | 15:25 15:53 | — | +28 | Departed |
| 15:45 | S089 | Slok Air Gambia | From Juan Manuel Gálvez International Airport RTB | 15:00 | 15:45 15:13 | -32 | Arrived |
| 16:00 | S065 | Slok Air Gambia | To Golosón International Airport LCE | 16:00 16:09 | — | +9 | Departed |
| 16:00 | S086 | Slok Air Gambia | To Juan Manuel Gálvez International Airport RTB | 16:00 | — | — | Not reported |
| 16:00 | W85236 | Cargojet Airways | To Miami International Airport MIA | 16:00 | — | — | Cancelled |
| 17:15 | H53015 | ALL / N/A | From Toncontín Airport TGU | 16:30 | 17:15 | — | Scheduled |
| 21:38 | UA1474 | United Airlines | From Newark Liberty International Airport EWR | 19:01 | 21:38 19:27 | -131 | Arrived |
| 21:57 | UA432 | United Airlines | From George Bush Intercontinental Airport IAH | 20:10 | 21:57 21:50 | -7 | Arrived |
| 23:10 | UA2450 | United Airlines | To Newark Liberty International Airport EWR | 23:10 | — | — | Cancelled |
| 23:25 | AV574 | Avianca | From El Salvador International Airport Saint Óscar Arnulfo Romero y Galdámez SAL | 22:30 | 23:25 | — | Cancelled |
| 23:25 | TA574 | Avianca El Salvador | From El Salvador International Airport Saint Óscar Arnulfo Romero y Galdámez SAL | 22:30 | 23:25 23:18 | -7 | Arrived |
| 23:29 | CM457 | Copa Airlines | From Tocumen International Airport PTY | 22:19 | 23:29 | — | Arrived |