| 03:13 | CM710 | Copa Airlines | To Tocumen International Airport PTY | 03:13 03:16 | — | +3 | Departed |
| 05:25 | AV314 | Avianca | To El Salvador International Airport Saint Óscar Arnulfo Romero y Galdámez SAL | 05:25 05:25 | — | 0 | Departed |
| 05:25 | TA314 | Avianca El Salvador | To El Salvador International Airport Saint Óscar Arnulfo Romero y Galdámez SAL | 05:25 05:15 | — | -10 | Departed |
| 06:35 | LC506 | Legend Airlines | From Juan Santamaría International Airport SJO | 05:15 | 06:35 | — | Not reported |
| 07:00 | LC142 | Legend Airlines | To Bluefields Airport BEF | 07:00 06:54 | — | -6 | Departed |
| 08:20 | RZ1060 | Sansa | From Juan Santamaría International Airport SJO | 07:00 | 08:20 08:15 | -5 | Arrived |
| 08:25 | AV396 | Avianca | From El Salvador International Airport Saint Óscar Arnulfo Romero y Galdámez SAL | 07:30 | 08:25 | — | Scheduled |
| 08:25 | TA396 | Avianca El Salvador | From El Salvador International Airport Saint Óscar Arnulfo Romero y Galdámez SAL | 07:30 | 08:25 08:09 | -16 | Arrived |
| 09:05 | RZ1061 | Sansa | To Juan Santamaría International Airport SJO | 09:05 08:50 | — | -15 | Departed |
| 09:25 | AV396 | Avianca | To Miami International Airport MIA | 09:25 | — | — | Cancelled |
| 09:25 | TA396 | Avianca El Salvador | To Miami International Airport MIA | 09:25 09:14 | — | -11 | Departed |
| 09:30 | LC1430 | Legend Airlines | From Corn Island Airport RNI | 08:20 | 09:30 | — | Not reported |
| 09:30 | LC1431 | Legend Airlines | From Bluefields Airport BEF | 08:45 | 09:30 | — | Not reported |
| 09:32 | 5X370 | United Parcel Service | From Miami International Airport MIA | 09:10 | 09:32 09:29 | -3 | Arrived |
| 09:45 | LC143 | Legend Airlines | From Bluefields Airport BEF | 08:45 | 09:45 | — | Scheduled |
| 10:00 | VTM680 | Air Tahiti | To Plan de Guadalupe International Airport SLW | 10:00 | — | — | Cancelled |
| 10:30 | LC134 | Legend Airlines | To Puerto Cabezas Airport PUZ | 10:30 10:08 | — | -22 | Departed |
| 11:11 | M6839 | Amerijet International | From Miami International Airport MIA | 10:50 | 11:11 09:49 | -82 | Arrived |
| 11:23 | AA309 | American Airlines | From Miami International Airport MIA | 10:37 | 11:23 10:34 | -49 | Arrived |
| 11:30 | 5D650 | Dutchbird | From Mexico City Benito Juárez International Airport MEX | 08:35 | 11:30 11:18 | -12 | Arrived |
| 11:30 | AM650 | Aeroméxico | From Mexico City Benito Juárez International Airport MEX | 08:35 | 11:30 | — | Cancelled |
| 11:53 | CM380 | Copa Airlines | From La Aurora International Airport GUA | 10:32 | 11:53 11:24 | -29 | Arrived |
| 12:06 | UA1432 | United Airlines | From George Bush Intercontinental Airport IAH | 09:50 | 12:06 09:12 | -174 | Arrived |
| 12:23 | AA340 | American Airlines | To Miami International Airport MIA | 12:23 13:05 | — | +42 | Departed |
| 12:30 | 5D651 | Dutchbird | To Mexico City Benito Juárez International Airport MEX | 12:30 12:39 | — | +9 | Departed |
| 12:30 | AM651 | Aeroméxico | To Mexico City Benito Juárez International Airport MEX | 12:30 | — | — | Scheduled |
| 12:49 | CM106 | Copa Airlines | From Tocumen International Airport PTY | 12:04 | 12:49 12:49 | 0 | Arrived |
| 13:15 | LC135 | Legend Airlines | From Puerto Cabezas Airport PUZ | 12:00 | 13:15 13:20 | +5 | Arrived |
| 13:20 | UA1433 | United Airlines | To George Bush Intercontinental Airport IAH | 13:20 13:25 | — | +5 | Departed |
| 13:47 | CM105 | Copa Airlines | To Tocumen International Airport PTY | 13:47 13:58 | — | +11 | Departed |
| 14:00 | LC148 | Legend Airlines | To Corn Island Airport RNI | 14:00 13:08 | — | -52 | Departed |
| 14:04 | CM361 | Copa Airlines | To La Aurora International Airport GUA | 14:04 14:08 | — | +4 | Departed |
| 14:09 | LC305 | Legend Airlines | To Juan Santamaría International Airport SJO | 14:09 14:19 | — | +10 | Departed |
| 14:20 | AV397 | Avianca | From Miami International Airport MIA | 13:45 | 14:20 | — | Scheduled |
| 14:20 | TA397 | Avianca El Salvador | From Miami International Airport MIA | 13:45 | 14:20 14:12 | -8 | Arrived |
| 15:15 | AV397 | Avianca | To El Salvador International Airport Saint Óscar Arnulfo Romero y Galdámez SAL | 15:15 | — | — | Cancelled |
| 15:15 | TA397 | Avianca El Salvador | To El Salvador International Airport Saint Óscar Arnulfo Romero y Galdámez SAL | 15:15 15:21 | — | +6 | Departed |
| 17:00 | LC149 | Legend Airlines | From Corn Island Airport RNI | 15:40 | 17:00 15:52 | -68 | Arrived |
| 18:30 | AV450 | Avianca | From El Salvador International Airport Saint Óscar Arnulfo Romero y Galdámez SAL | 17:35 | 18:30 | — | Cancelled |
| 18:30 | TA450 | Avianca El Salvador | From El Salvador International Airport Saint Óscar Arnulfo Romero y Galdámez SAL | 17:35 | 18:30 18:09 | -21 | Arrived |
| 19:30 | AV450 | Avianca | To Miami International Airport MIA | 19:30 | — | — | Cancelled |
| 19:30 | TA450 | Avianca El Salvador | To Miami International Airport MIA | 19:30 19:16 | — | -14 | Departed |
| 19:35 | LC306 | Legend Airlines | From Juan Santamaría International Airport SJO | 18:09 | 19:35 | — | Not reported |
| 20:10 | LC505 | Legend Airlines | To Juan Santamaría International Airport SJO | 20:10 | — | — | Not reported |
| 20:10 | M6839 | Amerijet International | From Miami International Airport MIA | 19:30 | 20:10 | — | Cancelled |
| 21:40 | M6838 | Amerijet International | To Miami International Airport MIA | 21:40 | — | — | Cancelled |
| 22:08 | CM712 | Copa Airlines | From Tocumen International Airport PTY | 21:26 | 22:08 | — | Cancelled |
| 23:00 | AV315 | Avianca | From El Salvador International Airport Saint Óscar Arnulfo Romero y Galdámez SAL | 22:05 | 23:00 | — | Cancelled |
| 23:00 | TA315 | Avianca El Salvador | From El Salvador International Airport Saint Óscar Arnulfo Romero y Galdámez SAL | 22:05 | 23:00 22:31 | -29 | Arrived |