| 03:13 | CM710 | Copa Airlines | To Tocumen International Airport PTY | 03:13 03:21 | — | +8 | Departed |
| 05:25 | AV314 | Avianca | To El Salvador International Airport Saint Óscar Arnulfo Romero y Galdámez SAL | 05:25 | — | — | Cancelled |
| 05:25 | TA314 | Avianca El Salvador | To El Salvador International Airport Saint Óscar Arnulfo Romero y Galdámez SAL | 05:25 05:12 | — | -13 | Departed |
| 07:00 | LC142 | Legend Airlines | To Bluefields Airport BEF | 07:00 06:51 | — | -9 | Departed |
| 08:20 | RZ1060 | Sansa | From Juan Santamaría International Airport SJO | 07:00 | 08:20 08:00 | -20 | Arrived |
| 08:25 | AV396 | Avianca | From El Salvador International Airport Saint Óscar Arnulfo Romero y Galdámez SAL | 07:30 | 08:25 | — | Cancelled |
| 08:25 | TA396 | Avianca El Salvador | From El Salvador International Airport Saint Óscar Arnulfo Romero y Galdámez SAL | 07:30 | 08:25 08:08 | -17 | Arrived |
| 08:47 | WH916 | WebJet Linhas Aéreas | From Tocumen International Airport PTY | 08:00 | 08:47 08:49 | +2 | Arrived |
| 09:05 | RZ1061 | Sansa | To Juan Santamaría International Airport SJO | 09:05 08:45 | — | -20 | Departed |
| 09:25 | AV396 | Avianca | To Miami International Airport MIA | 09:25 | — | — | Cancelled |
| 09:25 | TA396 | Avianca El Salvador | To Miami International Airport MIA | 09:25 09:13 | — | -12 | Departed |
| 09:30 | LC1430 | Legend Airlines | From Corn Island Airport RNI | 08:20 | 09:30 | — | Scheduled |
| 09:30 | LC1431 | Legend Airlines | From Bluefields Airport BEF | 08:45 | 09:30 | — | Scheduled |
| 09:38 | 5X370 | United Parcel Service | From Miami International Airport MIA | 09:10 | 09:38 10:01 | +23 | Arrived |
| 09:45 | LC143 | Legend Airlines | From Bluefields Airport BEF | 08:45 | 09:45 10:03 | +18 | Arrived |
| 10:02 | WH916 | WebJet Linhas Aéreas | To El Salvador International Airport Saint Óscar Arnulfo Romero y Galdámez SAL | 10:02 09:56 | — | -6 | Departed |
| 10:24 | CM818 | Copa Airlines | From Juan Santamaría International Airport SJO | 09:17 | 10:24 | — | Cancelled |
| 10:30 | LC134 | Legend Airlines | To Puerto Cabezas Airport PUZ | 10:30 09:40 | — | -50 | Departed |
| 11:23 | AA309 | American Airlines | From Miami International Airport MIA | 10:37 | 11:23 10:07 | -76 | Arrived |
| 11:30 | 5D650 | Dutchbird | From Mexico City Benito Juárez International Airport MEX | 08:35 | 11:30 11:06 | -24 | Arrived |
| 11:30 | AM650 | Aeroméxico | From Mexico City Benito Juárez International Airport MEX | 08:35 | 11:30 | — | Cancelled |
| 11:53 | CM380 | Copa Airlines | From La Aurora International Airport GUA | 10:32 | 11:53 11:21 | -32 | Arrived |
| 12:06 | UA1432 | United Airlines | From George Bush Intercontinental Airport IAH | 09:50 | 12:06 10:37 | -89 | Arrived |
| 12:23 | AA340 | American Airlines | To Miami International Airport MIA | 12:23 12:31 | — | +8 | Departed |
| 12:30 | 5D651 | Dutchbird | To Mexico City Benito Juárez International Airport MEX | 12:30 12:42 | — | +12 | Departed |
| 12:30 | AM651 | Aeroméxico | To Mexico City Benito Juárez International Airport MEX | 12:30 12:40 | — | +10 | Departed |
| 12:49 | CM106 | Copa Airlines | From Tocumen International Airport PTY | 12:04 | 12:49 12:38 | -11 | Arrived |
| 13:15 | LC135 | Legend Airlines | From Puerto Cabezas Airport PUZ | 12:00 | 13:15 13:01 | -14 | Arrived |
| 13:20 | UA1433 | United Airlines | To George Bush Intercontinental Airport IAH | 13:20 13:16 | — | -4 | Departed |
| 13:47 | CM105 | Copa Airlines | To Tocumen International Airport PTY | 13:47 13:53 | — | +6 | Departed |
| 14:00 | LC148 | Legend Airlines | To Corn Island Airport RNI | 14:00 13:40 | — | -20 | Departed |
| 14:04 | CM361 | Copa Airlines | To La Aurora International Airport GUA | 14:04 14:02 | — | -2 | Departed |
| 14:20 | AV397 | Avianca | From Miami International Airport MIA | 13:45 | 14:20 | — | Cancelled |
| 14:20 | TA397 | Avianca El Salvador | From Miami International Airport MIA | 13:45 | 14:20 14:11 | -9 | Arrived |
| 15:15 | AV397 | Avianca | To El Salvador International Airport Saint Óscar Arnulfo Romero y Galdámez SAL | 15:15 | — | — | Cancelled |
| 15:15 | TA397 | Avianca El Salvador | To El Salvador International Airport Saint Óscar Arnulfo Romero y Galdámez SAL | 15:15 15:11 | — | -4 | Departed |
| 15:49 | CM839 | Copa Airlines | To Juan Santamaría International Airport SJO | 15:49 15:52 | — | +3 | Departed |
| 15:55 | CM661 | Copa Airlines | From Tocumen International Airport PTY | 15:10 | 15:55 15:36 | -19 | Arrived |
| 17:00 | LC149 | Legend Airlines | From Corn Island Airport RNI | 15:40 | 17:00 15:49 | -71 | Arrived |
| 17:03 | CM662 | Copa Airlines | To Tocumen International Airport PTY | 17:03 16:48 | — | -15 | Departed |
| 18:30 | AV450 | Avianca | From El Salvador International Airport Saint Óscar Arnulfo Romero y Galdámez SAL | 17:35 | 18:30 | — | Cancelled |
| 18:30 | TA450 | Avianca El Salvador | From El Salvador International Airport Saint Óscar Arnulfo Romero y Galdámez SAL | 17:35 | 18:30 18:24 | -6 | Arrived |
| 19:30 | AV450 | Avianca | To Miami International Airport MIA | 19:30 19:40 | — | +10 | Departed |
| 19:30 | TA450 | Avianca El Salvador | To Miami International Airport MIA | 19:30 19:17 | — | -13 | Departed |
| 20:00 | VTM290 | Air Tahiti | To Monterrey International Airport MTY | 20:00 | — | — | Scheduled |
| 22:08 | CM712 | Copa Airlines | From Tocumen International Airport PTY | 21:26 | 22:08 21:59 | -9 | Arrived |
| 23:00 | AV315 | Avianca | From El Salvador International Airport Saint Óscar Arnulfo Romero y Galdámez SAL | 22:05 | 23:00 | — | Cancelled |
| 23:00 | TA315 | Avianca El Salvador | From El Salvador International Airport Saint Óscar Arnulfo Romero y Galdámez SAL | 22:05 | 23:00 22:44 | -16 | Arrived |